| Autor: |
Raquel, Núñez Aragón, Maria Luisa, Pedro-Botet Montoya, Lourdes, Mateu Pruñonosa, Nuria, Vallejo Camazón, Nieves, Sopena Galindo, Irma, Casas García, Sonia, Molinos Arbós, Miquel, Sabrià Leal |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Enfermedades infecciosas y microbiologia clinica. 31(1) |
| ISSN: |
1578-1852 |
| Popis: |
The primary aim of this study was to evaluate associated factors, clinical features and prognosis of healthcare-related infective endocarditis cases compared with community-acquired and intravenous drug user-related episodes. Changes in the distribution of healthcare-related infective endocarditis were also analysed over time in our setting.A prospective, observational, comparative study was performed. We included all the cases of infective endocarditis from January 2003 to June 2010, which were then classified into 2 groups: group 1: community-acquired and intravenous drug user origin, and group 2: nosocomial and non-nosocomial healthcare-related cases. The episodes were classified into 2 periods: period I: January/2003-June/2006 and period II: July/2006-June 2010. Univariate and multivariate analyses were performed.A total of 212 cases were included (group 1: 138, group 2: 74). The variables of age (risk ratio 1.026; 95%CI, 1.003 to 1.049), Charlson index (risk radio 1.242; 95%CI, 1.067 to 1.445), and previous heart surgery (risk ratio 2.522; 95%CI, 1.353 to 4.701) were independently associated with healthcare-related infective endocarditis on multivariate analysis. A non-significant increase was observed in healthcare-related cases of infective endocarditis in period II (40/104; 38.4% vs. 34/108; 31.4%).The recent increase in healthcare-related infective endocarditis seems to be associated with the use of invasive procedures in elderly patients with prosthetic cardiac valve, and those with a greater number of underlying diseases, especially patients with chronic renal failure on haemodialysis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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