[Platelet aggregation induced by fibrinmonomer and the effect of the heparin-adrenaline complex or plasmin on this process]

Autor: V E, Pastorova, L A, Liapina, B A, Kudriashov, E V, Lugovskoĭ
Rok vydání: 1990
Předmět:
Zdroj: Gematologiia i transfuziologiia. 35(7)
ISSN: 0234-5730
Popis: Addition of purified fibrin-monomer in a concentration of 0.5 mg/ml induces aggregation in a suspension of washed rat platelets in the absence of aggregants. Maximum aggregation takes place 1-3 min after fibrin-monomer addition, and then the disaggregation phase follows. Complex heparin compounds with adrenalin or plasmin possessing antipolymerization and fibrinolytic activity with respect to ++non-stabilized fibrin prevent, or to a great extent decrease fibrin-monomer-induced aggregation of washed platelets.
Databáze: OpenAIRE