[Significance of lacrimal fluid peroxidation and anti-radical defense parameters for prediction and treatment of complicated myopia]

Autor: M I, Vinetskaia, E N, Iomdina, E P, Tarutta, N Iu, Kushnarevich, A V, Lazuk
Rok vydání: 2001
Předmět:
Zdroj: Vestnik oftalmologii. 116(5)
ISSN: 0042-465X
Popis: Study of lipid peroxidation and antiradical defense parameters in the lacrimal fluid from 270 eyes of children and adolescents with progressive myopia demonstrated a relationship between the development of peripheral vitreochorioretinal dystrophies and imbalance between antioxidant activity (AOA) of lacrimal fluid and intensity of radical formation evaluated by chemiluminescence (CL) intensity. The AOA/CL ratio is proposed as a reliable indicator for predicting the course of progressive myopia. A value30 indicates poor level of antioxidant defense of ocular media and tissues and is a prognostically unfavorable sign as regards development of peripheral vitreochorioretinal dystrophy. A local antioxidant remedy has been developed and clinically tried for preventing and treating complicated myopia: ocular medicinal films with emoxipin and pyridoxine hydrochloride.
Databáze: OpenAIRE