Identification of a regulatory allele of teashirt (tsh) in Drosophila melanogaster that affects wing hinge development. An adult-specific tsh enhancer in Drosophila

Autor:	K H, Soanes, J O, MacKay, N, Core, T, Heslip, S, Kerridge, J B, Bell
Rok vydání:	2001
Předmět:	Models Anatomic Repressor Proteins Drosophila melanogaster Enhancer Elements Genetic Phenotype Time Factors Models Genetic Animals Drosophila Proteins Wings Animal Immunohistochemistry Alleles Transcription Factors
Zdroj:	Mechanisms of development. 105(1-2)
ISSN:	0925-4773
Popis:	A cis-acting regulatory element defined herein is required to drive teashirt (tsh) expression in the regions of the developing adult that give rise to proximal wing and haltere tissues. Loss of this expression results in the fusion of the proximal structures of the wing and halteres to the thoracic cuticle. This represents the first description of a viable adult-specific regulatory allele of tsh with a visible phenotype, and it enlarges our understanding of the expression of tsh and its function during the development of the adult.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ddba71223cff49ae42fc632c8b4197f3 https://pubmed.ncbi.nlm.nih.gov/11429289 Zobrazit plný text záznamu Full Text from ScienceDirect