Devic's syndrome and mixed connective tissue disease: an unusual association

Autor: Samila Alves, Silva, Patrícia Silva, Cunha, Araceli Santos, Brito, Rosana Barros, Souza, Sandra Lúcia Euzébio, Ribeiro
Rok vydání: 2018
Předmět:
Zdroj: Acta reumatologica portuguesa. 43(2)
ISSN: 2184-8777
Popis: Devic's disease or neuromyelitis optica (NMO) is an autoimmune, inflammatory and demyelinating pathology of the central nervous system that affects the optic nerve and the spinal cord. Diagnosis confirmed by imaging, magnetic resonance (MR) and the presence of the anti-aquaporin 4 antibody (anti-AQP4). We describe two cases of patients with mixed connective tissue disease (MCTD) and Devic's disease, who had anti-AQP4 positive and areas with neuroaxis MR abnormalities, showing this rare association.
Databáze: OpenAIRE