[Prognosis and Related Factors of Patients with Pathological Complete Response after Neoadjuvant Therapy for Gastric Cancer]

Autor: Tong-Bo, Wang, Hong, Zhou, Xiao-Jie, Zhang, Chong-Yuan, Sun, Chun-Guang, Guo, Ying-Tai, Chen, Ai-Ping, Zhou, Jing, Jin, Dong-Bing, Zhao
Rok vydání: 2021
Předmět:
Zdroj: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 43(4)
ISSN: 1000-503X
Popis: Objective To investigate the related factors of pathological complete response(pCR)of patients with gastric cancer treated by neoadjuvant therapy and resection,and to analyze the risk factors of prognosis. Methods The clinical and pathological data of 490 patients with gastric cancer who received neoadjuvant therapy followed by radical gastrectomy from January to December in 2008 were retrospectively analyzed.Univariate and multivariate analyses were performed to identify the risk factors affecting pCR and prognosis. Results Among the 490 patients,41 achieved pCR,and the overall pCR rate was 8.3%(41/490).The pCR rate was 16.0% in the neoadjuvant chemoradiation group and 6.4% in the neoadjuvant chemotherapy group.The results of multivariate analysis showed that neoadjuvant chemoradiation(
Databáze: OpenAIRE