The features and clinical outcomes of inflammatory bowel disease associated with autoimmune pancreatitis
| Autor: | Conti Bellocchi, Maria Cristina, Marconato, Eugenio, Lamonaca, Laura, Cattani Mottes, Martina, Ciccocioppo, Rachele, Carrara, Silvia, de Pretis, Nicolo’, Gabbrielli, Armando, Crinò, Stefano Francesco, Frulloni, Luca |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
Male diagnosis Autoimmune Pancreatitis Observational Study clinical outcome Middle Aged Inflammatory Bowel Diseases autoimmune pancreatitis inflammatory bowel diseases Italy Acute Disease Prevalence Humans Colitis Ulcerative Female Leukocyte L1 Antigen Complex Research Article ulcerative colitis Aged Retrospective Studies |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | The prevalence of inflammatory bowel disease (IBD) has been described in 5% to 40% of autoimmune pancreatitis (AIP) patients. The aim of our study was to evaluate the prevalence, endoscopic features, and outcome of IBD in association with AIP. A retrospective analysis including all consecutive patients with AIP and a histological diagnosis of IBD from 2010 to 2020 was performed. Demographical data, AIP, and IBD features, as well as clinical course, were recorded. Among 267 AIP patients, 45 were diagnosed with ulcerative colitis (UC) (27 men, mean age 31.6), all with a diagnosis of type 2 AIP. The most frequent presentation of AIP was acute pancreatitis (55.5%). Both diffuse (51.1%) and focal (48.9%) pancreatic involvement were observed. The AIP relapse rate was 11.1% over a mean follow-up of 55 months. In 69% of patients, the interval time between the diagnosis of AIP and UC was |
| Databáze: | OpenAIRE |
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