| Autor: |
K J, Smith, H G, Skelton, J, Yeager, P, Angritt, D, Frisman, K F, Wagner, D, Baxter, W D, James, C N, Oster |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Journal of the American Academy of Dermatology. 28(2 Pt 1) |
| ISSN: |
0190-9622 |
| Popis: |
Cutaneous lesions are common in patients with human immunodeficiency virus type 1 (HIV-1) infection. In many cases they are nonspecific inflammatory dermatoses.Our goal was to determine whether features of these inflammatory dermatoses were characteristic of HIV-1 infection and whether the changes correlated with the stage of disease.Biopsy specimens of inflammatory dermatoses from 176 HIV-1-infected patients in all Walter Reed stages were reviewed and the changes were compared with each WR stage.The changes found were nonspecific but were suggestive of features described in graft-versus-host disease and became more prominent in late-stage disease.A correlation was found between the changes and the stage of disease, and the findings add support to prior reports that at least some of the changes in HIV-1 infection may be autoimmune in origin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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