| Autor: |
Jashin J, Wu, Kathleen E, Gilbert, Michael, Batech, Iviensan F, Manalo, William J, Towner, Rui André Saraiva, Raposo, Douglas F, Nixon, Wilson, Liao |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Journal of drugs in dermatology : JDD. 16(4) |
| ISSN: |
1545-9616 |
| Popis: |
pBACKGROUND: HIV-associated psoriasis is well-documented. Genetic, cellular, and cytokine profiles have been used as evidence to suggest psoriasis activates antiviral pathways. There has been a lack of epidemiologic evidence investigating whether psoriasis patients have lower HIV viral counts compared to non-psoriasis patients./ppOBJECTIVE: Compare the viral load set point of HIV positive patients with and without psoriasis./ppMETHODS: A retrospective matched cohort study of HIV positive patients with and without psoriasis using the Kaiser Permanente Southern California Health Plan database./ppRESULTS: We identified 101 HIV-positive psoriasis cases; 19 met inclusion criteria and were matched with 3-5 control patients; 94 total patients were analyzed. The mean age was 41.4 (12.07) years and 83% were male. Overall, the median log of the viral load of cases was slightly higher than controls (4.3 vs 4.2; P less than 0.01)./ppCONCLUSIONS: The serum viral load set point of patients with HIV and psoriasis was slightly higher than the viral load set point of HIV patients without psoriasis./ppemJ Drugs Dermatol. 2017;16(4):372-377./em/p. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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