| Autor: |
J M, Wood, U, Dunleavy, R W, Newman, A M, Riley, J S, Robertson, P D, Minor |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Developments in biological standardization. 98 |
| ISSN: |
0301-5149 |
| Popis: |
Conventional influenza vaccines are standardised using the single-radial-immunodiffusion (SRD) test where reagents are produced from egg-grown viruses. It is important to ensure homology between SRD antigen reagents and test vaccines. There was concern that cell-grown vaccines may differ antigenically from corresponding egg-grown vaccines, which may in turn affect vaccine standardisation. In an examination of five cell-grown vaccines from two companies, only one vaccine was affected by the specificity of the SRD test. Options for standardisation of cell-grown vaccines are considered and recommendations are made for further studies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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