Popis: |
Eight newly synthesized compounds--fluorenyliden derivatives have been studied for their antibacterial activity as to M. tuberculosis H37Rv and different kinds of atypical bacteria. The expressed antimicrobial activity in vitro of 5-[(fluorenyliden-3-hydrason)-aminomethyl]-thioglycolic acid (IR-95.6), lithium salt (fluorenyliden-5-aminomethyl)-thioglycolic acid (LI-15), lithium salt (fluorenyliden-9-hydraside)-thioglycolic acid (LI-75), with respect to M. tuberculosis H37Rv and considerable bacteriostatic action of all the studied substances as to M. fortuitum 23 have been established. |