Intravenous versus subcutaneous vitamin K1 in reversing excessive oral anticoagulation

Autor:	R, Nee, D, Doppenschmidt, D J, Donovan, T C, Andrews
Rok vydání:	1999
Předmět:	Adult Analysis of Variance Dose-Response Relationship Drug Injections Subcutaneous Injections Intravenous Anticoagulants Humans International Normalized Ratio Vitamin K 1 Warfarin Blood Coagulation Antifibrinolytic Agents
Zdroj:	The American journal of cardiology. 83(2)
ISSN:	0002-9149
Popis:	Our data suggest that compared with the subcutaneous route of administration, intravenous vitamin K1 results in a more prompt reduction in the international normalized ration. However, for most patients, subcutaneous vitamin K1 is an effective and safe alternative when used in conjunction with modification of subsequent warfarin dosing, because virtually all patients achieved a safe level of anticoagulation within 72 hours with this route of administration.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::db4db99e9389ab701bb1f252bb998f1a https://pubmed.ncbi.nlm.nih.gov/10073841 Zobrazit plný text záznamu Full Text from ScienceDirect