| Autor: |
Yanai, Douglas, Lakhanpal, Rohit R, Weiland, James D, Mahadevappa, Manjunatha, Van Boemel, Gretchen, Fujii, Gildo Y, Greenberg, Robert, Caffey, Sean, de Juan, Eugene, Humayun, Mark S |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
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| Popis: |
PURPOSE: To determine the best candidates (ie, those requiring lowest current levels delivered to the retina to elicit visual perceptions) for long-term implantation of a microelectronic retinal implant through a series of preoperative visual, psychophysical, and electrophysiological tests. METHODS: This study protocol was granted an investigational device exemption by the Food and Drug Administration and was approved by the institutional review board at the University of Southern California. After informed consent was obtained, all subjects underwent the following preoperative tests: dark-adapted bright flash and 30-Hz flicker electroretinograms, electrical evoked responses (EERs) using a Burian-Allen corneal electrode to stimulate the globe, and psychophysical tests to evaluate the light and electrically elicited visual perceptions. Intraocular stimulation (IOS) of the retina was performed by an array of electrodes positioned on the internal limiting lamina. RESULTS: Lower vision correlated with less sensitive psychophysical responses (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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