| Autor: |
G E, Childs, L, Pang, T, Wimonwattrawatee, N, Pooyindee, A, Nanakorn, S, Limchitee, H K, Webster |
| Rok vydání: |
1987 |
| Předmět: |
|
| Zdroj: |
The Southeast Asian journal of tropical medicine and public health. 18(4) |
| ISSN: |
0125-1562 |
| Popis: |
The in vitro susceptibility of twenty isolates of Plasmodium falciparum from Tha Song Yang, Tak province, Thailand were determined. The isolates were resistant to chloroquine (IC50 = 220 nM; MIC = 762 nM), quinine (IC50 = 252 nM; MIC = 1010 nM), and pyrimethamine (IC50 = 16400 nM; MIC = 43100 nM) but generally sensitive to mefloquine (IC50 = 6.90 nM; MIC = 20.9 nM) and halofantrine (IC50 = 8.73 nM; MIC = 2.71 nM). Two isolates were identified which appeared resistant to mefloquine (IC50 = 23.1 nM; MIC = 56.6 nM). These isolates may represent an extension of a population of parasites from eastern Thailand. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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