| Autor: |
Shahram, Ghanaati, Mike, Barbeck, Ines, Willershausen, Benjamin, Thimm, Stefan, Stuebinger, Tadas, Korzinskas, Karina, Obreja, Constantin, Landes, Charles J, Kirkpatrick, Robert A, Sader |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Clinical implant dentistry and related research. 15(6) |
| ISSN: |
1708-8208 |
| Popis: |
In this study the de novo bone formation capacity of a nanocrystalline hydroxyapatite bone substitute was assessed 3 and 6 months after its insertion into the human sinus cavity.Sinus cavity augmentation was performed in a total of 14 patients (n = 7 implantation after 3 months; n = 7 implantation after 6 months) with severely atrophic maxillary bone. The specimens obtained after 3 and 6 months were analyzed histologically and histomorphometrically with special focus on bone metabolism within the residual bone and the augmented region.This study revealed that bone tissue formation started from the bone-biomaterial-interface and was directed into the most cranial parts of the augmented region. There was no statistically significant difference in new bone formation after 3 and 6 months (24.89 ± 10.22% vs 31.29 ± 2.29%), respectively.Within the limits of the present study and according to previously published data, implant insertion in regions augmented with this bone substitute material could be considered already after 3 months. Further clinical studies with bone substitute materials are necessary to validate these findings. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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