[Treatment of upper genital infections in women. Multicenter study of the comparative efficacy and tolerance of an amoxicillin-clavulanic acid combination and of a triple antibiotic combination]

Autor: P, Buisson, C, Mulard, J, Baudet, P, Bernard, P, Mares, M, Montero, M, Lerat, C, Quereux, J, Santarelli, C, Valette
Jazyk: francouzština
Rok vydání: 1989
Předmět:
Zdroj: Revue francaise de gynecologie et d'obstetrique. 84(10)
ISSN: 0035-290X
Popis: Eighty-two patients with laparoscopically confirmed salpingitis were randomly divided into two groups in a multicentre and prospective trial. Single drug therapy with the amoxicillin-clavulanic acid combination was used in 42 patients (group A). The other 40 patients were given a combination of penicillin, aminoside and metronidazole (group B). For each case a secondary prescription for a tetracycline was discussed. Clinical results were comparable in both groups: sooner (at the end of the hospitalization period) in group A: 10 cured, 30 improved and 2 failures against 9 cured, 30 improved in group B. Later (evaluation after 5 to 8 weeks) a relapse was noted in five patients in group A and included one case of angioedema in group B. It is concluded that amoxicillin-clavulanic acid combination is a satisfactory alternative to the penicillin-aminoside-metronidazole combination, especially as it is simpler to use.
Databáze: OpenAIRE