| Autor: |
H I, Huppertz, H, Karch, H J, Suschke, E, Döring, G, Ganser, A, Thon, W, Bentas |
| Rok vydání: |
1995 |
| Předmět: |
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| Zdroj: |
Arthritis and rheumatism. 38(3) |
| ISSN: |
0004-3591 |
| Popis: |
To evaluate and describe Lyme arthritis in European children and adolescents.This was a prospective multicenter study. The diagnosis of Lyme arthritis required the exclusion of other diseases and positive findings on serology for IgG antibodies to Borrelia burgdorferi. Enzyme-linked immunosorbent assay, immunoblotting, and polymerase chain reaction techniques to identify infection by B burgdorferi were used.Among 62 children and adolescents with Lyme arthritis, only 1 had a preceding erythema migrans. Arthritis was episodic in 62% and was chronic at onset in 18%. The most common manifestation was monarthritis of the knee. Joint involvement in patients with oligoarthritis was predominantly unilateral or symmetric. Arthralgia was very rare. Treatment with 1 or 2 courses of different antibiotics resulted in disappearance of the arthritis in 77% of the patients.The clinical presentation of Lyme arthritis in children is different from that in adults. The calculated incidence of Lyme arthritis in persons under the age of 17 years (4/100,000) exceeds previous estimations. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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