Fiberoptic bronchoscopy in the immunocompromised host: the significance of a 'nonspecific' transbronchial biopsy

Autor:	J N, Nishio, J P, Lynch
Rok vydání:	1980
Předmět:	Adult Immunosuppression Therapy Lung Diseases Male Leukemia Lung Neoplasms Biopsy Cytodiagnosis Pulmonary Fibrosis Bronchi Middle Aged Hodgkin Disease Radiography Bronchoscopy Carcinoma Squamous Cell Immune Tolerance Fiber Optic Technology Humans Female Lung Aged
Zdroj:	The American review of respiratory disease. 121(2)
ISSN:	0003-0805
Popis:	Fifty-eight flexible fiberoptic bronchoscopies were performed in 49 immunocompromised patients in the diagnostic evaluation of pulmonary infiltrates. Transbronchial lung biopsy (TBB) provided a specific diagnosis in only 12 of 47 procedures (26%). The addition of bronchial brushings to the procedures slightly increased the diagnostic yield. The yield of bronchial brushings was enhanced in patients with diffuse infiltrates on chest roentgenogram (P less than 0.05). Nonspecific inflammatory or fibrotic changes were the most common histologic finding on TBB when pulmonary parenchyma was obtained (found in 16 of 47 procedures, or 34%). Alternative specific etiologic diagnoses were established in 7 of these 16 cases by other diagnostic modalities. Contrary to previous reports, further evaluation of nonspecific changes on TBB may lead to changes in therapy and improved prognosis in selected patients. Complications related to the bronchoscopic procedures were infrequent and resulted in no prolonged morbidity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d91840cf1cb0adb67235e6c76ed41996 https://pubmed.ncbi.nlm.nih.gov/7362138 Zobrazit plný text záznamu