Guidelines on the clinical usefulness of determination of specific immunoglobulin E to foods
| Autor: | B E, García, P M, Gamboa, J A, Asturias, M, López-Hoyos, M L, Sanz, M T, Caballero, J M, García, M, Labrador, C, Lahoz, N, Longo Areso, J, Martínez Quesada, L, Mayorga, F J, Monteseirín |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Adolescent Administration Oral Comorbidity Sensitivity and Specificity Dermatitis Atopic Diagnosis Differential Epitopes Predictive Value of Tests Humans Serologic Tests Child Selection Bias Aged Aged 80 and over Infant Newborn Infant Rhinitis Allergic Seasonal Allergens Immunoglobulin E Middle Aged Prognosis Food Spain Child Preschool Feasibility Studies Female Immunization Algorithms Food Hypersensitivity |
| Zdroj: | Journal of investigational allergologyclinical immunology. 19(6) |
| ISSN: | 1018-9068 |
| Popis: | The diagnostic gold standard for food allergy is challenge with the culprit food, particularly in double-blind placebo-controlled challenge. This approach involves risks and consumes both time and resources. A more efficient system would be desirable. The detection of serum specific immunoglobulin E (sIgE) against the culprit food enables us to establish sensitization, although this is not always accompanied by clinical reactivity. Age, symptoms (immediate/late reaction, local/systemic reaction), concomitant condition (eg, atopic dermatitis, pollinosis) and selection sample criteria (eg, presence of symptoms related to ingestion, positive skin prick test result) can influence the detection and concentration of IgE against foods. We analyze the clinical usefulness of sIgE determination in light of studies in which oral food challenge is used as the diagnostic method. We review clinical usefulness at diagnosis and in the decision to reintroduce the food, as well as the prognostic value of the determination of IgE to foods. |
| Databáze: | OpenAIRE |
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