| Autor: |
T, Kakhniashvili, N, Tabagari-Bregvadze, Sh, Dzvelaia, A, Chikadze, R, Kurashvili |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Georgian medical news. (283) |
| ISSN: |
1512-0112 |
| Popis: |
Our aim was to compare serum vascular endothelial growth factor (VEGF) level in type 2 diabetes mellitus (T2DM) patients with comorbid OSA at screening and 6 month follow up visits. In the prospective cohort study following data were collected at screening visit: medical anamnesis; demographic and anthropometric data; Epworth sleepiness score data; laboratory (serum VEGF, complete blood count, biochemistry, immunology, complete urine test, including microalbuminuria) and instrumental investigation data (fundoscophy, laboratory polysomnography). At 6 months follow up visit we evaluated anthropometric data; Epworth sleepiness score; serum VEGF. Comparing VEGF level at screening and 6 month follow up visits showed significant decrease in VEGF level in both groups (P=0.0281 OSA+ and P=0.0278 OSA-). It was established direct correlation between decreased VEGF level and decreased HbA1c level (P=0.04696) and between decreased VEGF level and Epworth sleepiness score (P=0.0153) at 6 month follow up visit in OSA+ group. Our the study suggests that VEGF level decreases in parallel with diabetes compensation quality. Future researches are necessary to support this research. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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