| Autor: |
H, Sapper, W, Gohl, W, Lohmann |
| Jazyk: |
němčina |
| Rok vydání: |
1980 |
| Předmět: |
|
| Zdroj: |
Zeitschrift fur Naturforschung. Section C, Biosciences. 35(7-8) |
| ISSN: |
0341-0382 |
| Popis: |
The interaction between aromatic amines and ATP is based upon an electrostatic attraction of the protonated amino groups to the negatively charged phosphate groups of ATP combined with a stacking association between the ring systems. The complexes formed are relatively weak (association constants 4--48 M-1), shortlived (life time smaller than 0.02 s), and mainly 1:1 in stoichiometry preferring the terminal phosphate of ATP as the site of association. The divalent metal ions Mg2+ and Ca2+ bond stronger than the amines (association constants 1500 and 100 M-1, resp.) prefer the beta-phosphate group changing thereby the geometry of the ATP phosphate chain. Thus, they reduce the amine-ATP association in ternary mixtures. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
