[Prognostic factors and predictive tables of non-localized prostate cancer that exclude therapy by radical prostatectomy]

Autor: H, Villavicencio Mavrich, F, Millán Rodríguez, G, Chéchile Toniolo, D, Salinas Duffo, J, Vicente Rodríguez
Rok vydání: 1998
Předmět:
Zdroj: Actas urologicas espanolas. 22(7)
ISSN: 0210-4806
Popis: To know the predictive factors of the no localized prostatic cancer (NLPC) with the intention of improving the indications of the radical prostatectomy.A longitudinal, observational, analytic and retrospective study is made with our first 216 radical prostatectomies. A multivariate analysis by logistic regression has been made. A predictive evacuation with the odds ratio of the risc factors, a ROC curve and predictive tables of the NLPC are obtained.Clinical stage, PSA and Gleason are predictive factors of the NLPC. The predictive evacuation with a cut point of probability p = 0.5 has a specificity of 81%, a sensibility of 70% and global diagnostic capacity of 75%. NLCP odds ratio are: Gleason 5,6,7/Gleason 2,3,4 = 2.6, Gleason 8,9,10/Gleason 5,6,7 = 3, Gleason 8,9,10/Gleason 2,3,4 = 7.6, T2/T1 = 2, T3/T2 = 5, T3/T1 = 10 and PSA = 1. After the study of the predictive tables it can be concluded that T3, Gleason= 8 and PSA= 30 have a very high NLPC probability.PSA, Gleason and clinical stage are NLPC predictive factors. Predictive tables to know the NLPC probability by these 3 factors are available.
Databáze: OpenAIRE