[Echocardiographic findings, pro-ANP and treatment in acute myocardial infarction without overt heart failure]

Autor: J E, Otterstad, C, Hall, B, Graving, T, Skjaerpe, I, Holme
Rok vydání: 1999
Předmět:
Zdroj: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 119(19)
ISSN: 0029-2001
Popis: This study was undertaken to characterise patients without overt heart failure and with a left ventricular ejection fractionor = 40% 2-7 days following an acute myocardial infarction. Patients with an ejection fractionor = 40% (n = 868) had a lower prevalence of anterior myocardial infarction (p0.001) and lower levels of N-terminal pro-ANP (atrial natriuretic peptide) (p0.001) than those with ejection fraction40% (n = 305). Patients with ejection fractionor = 40% had smaller left ventricular volume and mass (p0.001). Pro-ANP levels did not correlate significantly with left ventricular volume or ejection fraction in this group. Among patients with ejection fraction40%; statistically significant correlations between pro-ANP levels and both ejection fraction and left ventricular endsystolic volume were found. 64% and 61% of patients in the two groups were given thrombolytic treatment. In this study, most patients with acute myocardial infarction had an ejection fractionor = 40%. Pro-ANP levels were not correlated with the ejection fraction or left ventricular volume. Approximately two thirds of the patients received thrombolytic treatment.
Databáze: OpenAIRE