Studies with the baboon endogenous virus and its pseudotype of murine sarcoma virus in marmosets

Autor: R L, Heberling, S S, Kalter, J W, Eichberg, B M, Levy
Rok vydání: 1978
Předmět:
Zdroj: Primates in medicine. 10
ISSN: 0079-5119
Popis: Three marmoset species (Saguinus oedipus oedipus, S. fuscicollis, Callithrix jacchus) failed to show evidence of infection or disease following inoculation of baboon endogenous type-C virus (BaEV). Cells infected with a Kirsten murine sarcoma-BaEV pseudotype (MSV[BaEV]) produced a progressive fibrosarcoma in S. o. oedipus and tumors in S. fuscicollis and C. jacchus which regressed. Tumor formation is believed to be due to growth of inoculated, virus-infected cells and not transformation of marmoset cells. S. o. oedipus showed the best serum neutralizing antibody response to BaEV and MSV(BaEV), S. fuscicollis a moderate response and C. jacchus no response.
Databáze: OpenAIRE