Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR

Autor:	Jiayi, Shen, Tao, Zhang, Su-Jie, Zhu, Min, Sun, Linjiang, Tong, Mengzhen, Lai, Rong, Zhang, Wei, Xu, Ruibo, Wu, Jian, Ding, Cai-Hong, Yun, Hua, Xie, Xiaoyun, Lu, Ke, Ding
Rok vydání:	2019
Předmět:	ErbB Receptors Molecular Docking Simulation Structure-Activity Relationship Pyridones Drug Design Mutation Humans Crystallography X-Ray Protein Structure Secondary Protein Structure Tertiary
Zdroj:	Journal of medicinal chemistry. 62(15)
ISSN:	1520-4804
Popis:	Tertiary EGFR
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d83b63e6bf6876908ecfd4567eda6202 https://pubmed.ncbi.nlm.nih.gov/31298540 Zobrazit plný text záznamu