[Neurochemical changes and current pharmacological approaches in craniocerebral trauma]

Autor:	T, Kossmann, P M, Lenzlinger, J F, Stover, R, Stocker, M C, Morganti-Kossmann, O, Trentz
Jazyk:	němčina
Rok vydání:	1997
Předmět:	Arachidonic Acid Brain Injuries Excitatory Amino Acids Head Injuries Closed Animals Humans Calcium Calcium Channel Blockers Energy Metabolism Reactive Oxygen Species Excitatory Amino Acid Antagonists Synaptic Transmission Antioxidants
Zdroj:	Der Unfallchirurg. 100(8)
ISSN:	0177-5537
Popis:	In recent years, our knowledge concerning pathophysiological changes in brain metabolism after traumatic brain injury (TBI) has greatly expanded. This, in turn, has enabled the development of specific pharmacological strategies for the supplementary treatment of brain-injured patients with the aim of reducing secondary brain damage. The present article focuses on the pathophysiology of TBI and the possibilities for pharmacological intervention. While some of the substances reviewed and presently used in the treatment of TBI, others are under experimental and clinical evaluation at different stages.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d81b8949485dc1c833b389be84220017 https://pubmed.ncbi.nlm.nih.gov/9381209 Zobrazit plný text záznamu Full text from SpringerLink