[Renal pathological characteristics in cirrhotic patients]
| Autor: | J L, You, R, Xu |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Zhonghua nei ke za zhi. 59(11) |
| ISSN: | 0578-1426 |
| Popis: | This study is aim to analyze pathological characteristics of kidneys in cirrhotic patients with renal disease. Fifty-six cirrhotic patients with various renal diseases at Peking University First Hospital who underwent percutaneous renal biopsy from January 2010 to September 2019 were evaluated retrospectively. Immunoglobulin A nephropathy (IgAN) was the most common type of kidney biopsy (23 cases, 41.1%). Different pathologic types were often overlapping. More than 60% patients were treated with steroids and/or immunosuppressants, and 1 patient with anti-CD20 monoclonal antibody. Percutaneous renal biopsy is important for the diagnosis and treatment in cirrhotic patients with renal disease.为了解肝硬化伴肾损害患者的肾脏病理类型，本研究回顾性分析2010年1月至2019年9月北京大学第一医院肾内科收治的56例肝硬化伴肾病患者的肾脏病理类型。56例患者的肾脏病理类型具有多样性及复杂性，多种病理类型可在同一患者中存在，其中以IgA肾病最常见（41.1%，23例）。39例患者在肾脏病理结果指导下调整了治疗方案，其中36例患者行糖皮质激素和/或免疫抑制剂治疗，1例患者行利妥昔单抗治疗，1例患者血液透析后肾功能恢复。肾组织活检对肝硬化伴肾病患者临床诊断及治疗有重要指导作用，肝硬化并非肾组织活检的禁忌证。. |
| Databáze: | OpenAIRE |
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