| Autor: |
T V, Boĭkova, V, Orlando, R, Lupo, S S, Bogachev |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Genetika. 41(11) |
| ISSN: |
0016-6758 |
| Popis: |
The bithorax (BX) complex of Drosophila is a complex polygenic region with a multifactorial system of regulation. One of the levels of the regulatory system of the BX complex is its association with the nuclear skeleton structures through a specific interaction of the M/SAR DNA with the nuclear matrix proteins. In the present work, M/SAR elements were mapped on the molecular-genetic map of the region. All of the elements examined were found to colocalize with regulatory elements and form clusters that restrict/bracket the genetically active domains. All M/SAR DNA revealed was shown to bins specifically to the purified Drosophila melanogaster lamin. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
