| Autor: |
B, Le Luyer, J F, Mougenot, L, Mashako, P, Chapoy, J P, Olives, A, Morali, B, Chevallier, J L, Ginies, C, Dupont, M, Dagorne |
| Jazyk: |
francouzština |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Archives francaises de pediatrie. 47(1) |
| ISSN: |
0003-9764 |
| Popis: |
Eighty-three children presenting with symptomatic gastro-esophageal reflux (GER) (48 males, 35 females, aged 15 days to 57 months (mean = 7 months) were assessed by pH monitoring. All showed acid pathological GER on the 3 hours post-prandial esophageal pH measurement (% of time at pH less than 4 greater than 4.2) and all had a second pH measurement within the following 3 hours after intake of a single (5 ml) dose of sodium alginate (AGS). AGS administration was followed by a highly significant reduction (p less than 0.00001) of all pH measurement variables: a) Percentage of time spent at pH less than 4 returned to normal with a mean 11.7% to 4.8%; that is a 52.5% improvement (median); b) Total number of reflux reduced on average from 8.9 to 5.0: that is a 35% improvement (median); c) Mean duration of reflux reduced on average for 4 to 2 min; that is a 60% improvement (median). In 76 patients hourly monitoring of % of time spent at pH less than 4 shows that hourly improvement persists. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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