[The diagnosis and clinical characteristics of cytomegalovirus infection in HIV-infected subjects]
| Autor: | V I, Shakhgil'dian, A V, Kravchenko, O Iu, Shipulina, N R, Marchenko, T N, Ermak, O G, Iurin, V M, Stakhanova, Iu G, Parkhomenko, N V, Karazhas, L F, Evseeva, B M, Gruzdev, V V, Pokrovskiĭ |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male AIDS-Related Opportunistic Infections Sialic Acid Binding Ig-like Lectin 2 Cytomegalovirus CD8-Positive T-Lymphocytes HIV Antibodies Middle Aged Urine CD4 Lymphocyte Count Antigens Differentiation B-Lymphocyte Antibody Specificity Antigens CD Lectins Cytomegalovirus Infections DNA Viral HIV-1 Humans Female Lymphocyte Count Cell Adhesion Molecules |
| Zdroj: | Terapevticheskii arkhiv. 68(4) |
| ISSN: | 0040-3660 |
| Popis: | Out of 180 HIV carriers active cytomegalovirus (CMV) infection was found in 30 patients, in 16 cases the infection manifested clinically. Most of the latter were patients with HIV infection IIIb or IIIc stage against persistent lowering of CD4-lymphocyte count under 100/mm3. Active CMV infection may be determined most significantly by the following criteria: high or moderate concentrations of CMV DNA in the blood, low concentrations of blood CMV DNA in the presence of long-term (at least 3 months) persistence of anti-CMV IgM and isolation of urinary CMV. CMV infection manifested usually as a generalized disease with typical signs of retinitis, myelitis, erosive-ulcerative colitis. Most patients had thrombocytopenia, functionally defective platelets. CNS involvement predicts poor prognosis in CMV-infected HIV carriers. |
| Databáze: | OpenAIRE |
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