HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19

Autor: Giorgio, Ciprandi, Luisa Maria, Bellussi, Valerio, Damiani, Desiderio, Passali
Rok vydání: 2021
Předmět:
Zdroj: Acta bio-medica : Atenei Parmensis. 92(S6)
ISSN: 2531-6745
Popis: The COVID-19 pandemic era is causing a relevant issue for the health. There is no specific drug able to antagonize the SARS-CoV-2 infection. As a consequence, there is growing interest about potential molecules able to contrast infection. In this regard, HMGB, an alarmin, may play a relevant role in pathogenic mechanisms induced by SARS-CoV-2. As HMGB1 is antagonized by glycyrrhizin, this substance could be potentially useful as ancillary treatment in COVID-19.
Databáze: OpenAIRE