HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19
Autor: | Giorgio, Ciprandi, Luisa Maria, Bellussi, Valerio, Damiani, Desiderio, Passali |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Acta bio-medica : Atenei Parmensis. 92(S6) |
ISSN: | 2531-6745 |
Popis: | The COVID-19 pandemic era is causing a relevant issue for the health. There is no specific drug able to antagonize the SARS-CoV-2 infection. As a consequence, there is growing interest about potential molecules able to contrast infection. In this regard, HMGB, an alarmin, may play a relevant role in pathogenic mechanisms induced by SARS-CoV-2. As HMGB1 is antagonized by glycyrrhizin, this substance could be potentially useful as ancillary treatment in COVID-19. |
Databáze: | OpenAIRE |
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