Autor: |
V, Recchi, S, Hieronimus, G, Creisson, P, Freychet, I, Morange, B, Canivet |
Jazyk: |
francouzština |
Rok vydání: |
1997 |
Předmět: |
|
Zdroj: |
La Revue de medecine interne. 18(4) |
ISSN: |
0248-8663 |
Popis: |
Macroprolactinemia, due to increased circulating levels of large molecular weight forms of prolactin, results in elevated level of immuno-reactive prolactin. The big variants have only weak biological activity; thus macroprolactinemia appears as a case of hyperprolactinemia without clinical significance as demonstrated by the five patients described. The diagnosis is based upon chromatography which separates the hormone and its variants. This disorder produces a pitfall in the diagnostic evaluation of hyperprolactinemia. |
Databáze: |
OpenAIRE |
Externí odkaz: |
|