| Autor: |
Evangelos, Konstantinidis, Agnieszka, Molisak, Florian, Perrin, Linn, Streubel-Gallasch, Sarah, Fayad, Daniel Y, Kim, Karl, Petri, Martin J, Aryee, Ximena, Aguilar, Bence, György, Vilmantas, Giedraitis, J Keith, Joung, Vikram, Pattanayak, Magnus, Essand, Anna, Erlandsson, Oksana, Berezovska, Martin, Ingelsson |
| Rok vydání: |
2021 |
| Zdroj: |
Molecular therapy. Nucleic acids. 28 |
| ISSN: |
2162-2531 |
| Popis: |
Presenilin 1 (PS1) is a central component of γ-secretase, an enzymatic complex involved in the generation of the amyloid-β (Aβ) peptide that deposits as plaques in the Alzheimer's disease (AD) brain. The M146L mutation in the PS1 gene ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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