Downregulation of fibrosis and inflammatory signalling pathways in rats liver
| Autor: | Basant M, Morsy, Manal A, Hamed, Howaida I, Abd-Alla, Wessam M, Aziz, Sally N, Kamel |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Inflammation
Male Ethanol Plant Extracts Superoxide Dismutase Down-Regulation Alanine Transaminase Plant Components Aerial Fibrosis Glutathione Pulicaria Rats Liver Animals Humans Aspartate Aminotransferases Chemical and Drug Induced Liver Injury Carbon Tetrachloride Phytotherapy Signal Transduction |
| Zdroj: | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 26(8) |
| ISSN: | 1366-5804 |
| Popis: | Liver is a vital organ for the detoxification of toxic substances in the body, where fibrosis is the major cause of liver damage.This study aimed to modulate the fibrosis and inflammatory signalling pathways in carbon tetrachloride (CClCClThe phytochemical analysis of the extract showed the presence of sterols and/or triterpenoids. Treatments with plant extract suppressed significantly (PCEE succeeded to exert anti-fibrotic, anti-inflammatory and anti- oxidants effects in CCl |
| Databáze: | OpenAIRE |
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