A vaccine prepared from a non-pathogenic H5N1 influenza virus strain from the influenza virus library conferred protective immunity to chickens against the challenge with antigenically drifted highly pathogenic avian influenza virus

Autor:	Rozanah Asmah Abdul, Samad, Naoki, Nomura, Yoshimi, Tsuda, Rashid, Manzoor, Masahiro, Kajihara, Daisuke, Tomabechi, Takashi, Sasaki, Norihide, Kokumai, Toshiaki, Ohgitani, Masatoshi, Okamatsu, Ayato, Takada, Yoshihiro, Sakoda, Hiroshi, Kida
Rok vydání:	2011
Předmět:	Influenza A Virus H5N1 Subtype Mongolia Cross Reactions Antibodies Viral Disease Outbreaks Ducks Antibody Specificity Influenza Vaccines Anseriformes Influenza in Birds DNA Viral Animals Chickens Reassortant Viruses
Zdroj:	The Japanese journal of veterinary research. 59(1)
ISSN:	0047-1917
Popis:	Inactivated influenza virus vaccine prepared from a non-pathogenic influenza virus strain A/duck/Hokkaido/Vac-1/2004 (H5N1) from the virus library conferred protective immunity to chickens against the challenge of antigenically drifted highly pathogenic avian influenza virus (HPAIV), A/whooper swan/Hokkaido/1/2008 (H5N1). The efficacy of the vaccine was comparable to that prepared from genetically modified HPAIV strain deltaRRRRK rg-A/ whooper swan/Mongolia/3/2005 (H5N1), which is more antigenically related to the challenge virus strain, in chickens.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d521c254a33f3918604b037c180960d1 https://pubmed.ncbi.nlm.nih.gov/21476487 Zobrazit plný text záznamu