[Regulation mechanism of variation in Plasmodium falciparum var gene family]

Autor: Qing-feng, Zhang, Wei-qing, Pan
Rok vydání: 2007
Předmět:
Zdroj: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitologyparasitic diseases. 25(4)
ISSN: 1000-7423
Popis: This is a review on the new progress in the study of regulation mechanism of Plasmodium falciparum Var gene family. The mutually exclusive expression system caused expression only one in 60 var genes while others were silenced. It was regulated on the transcriptional level mainly through three pathways: non-coding DNA elements, chromatin structure and perinuclear localization.
Databáze: OpenAIRE