| Autor: |
N M, Stadnikova, E V, Kleĭmenova, E P, Grankina, L N, Pylev |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Voprosy onkologii. 37(11-12) |
| ISSN: |
0507-3758 |
| Popis: |
Sodium selenite given in drinking water in a 4 ppm solution during the whole experiment was found to significantly inhibit pleural carcinogenesis induced in Wistar rats by intrapleural injection of chrysotile-asbestos powder (20 mg three times, monthly, in 0.5 ml of physiologic saline). Mesothelioma of the pleura was induced in 20.5%. However, chrysotile alone induced tumor in 43.8%. Sodium selenite failed to influence carcinogenesis in other sites. Possible mechanisms of sodium selenite action are discussed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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