[HER2-Positive Advanced Gastric Cancer with Para-Aortic Lymph Node Metastases Treated with Conversion Surgery after Chemotherapy-A Case Report]

Autor: Kohei, Furusawa, Masaharu, Higashida, Hisako, Kubota, Ryo, Iwamoto, Shuji, Kitagawa, Seiya, Kinoshita, Michi, Ueno, Shumei, Mineta, Yuko, Okamoto, Yusaku, Watanabe, Toshimasa, Okada, Atsushi, Tsuruta, Yoshinori, Fujiwara, Tomio, Ueno
Rok vydání: 2020
Předmět:
Zdroj: Gan to kagaku ryoho. Cancerchemotherapy. 46(13)
ISSN: 0385-0684
Popis: A 56-year-old woman diagnosed with type 2 gastric cancer and multiple lymph node metastases(T3N3M1[lym], cStage Ⅳ)was treated with chemotherapy using trastuzumab with S-1 plus cisplatin for 6 cycles. The primary lesion showed PR, and lymph node metastases disappeared after the chemotherapy. Because of adverse events, she was administered with 2 additional cycles of trastuzumab with S-1 plus cisplatin and 6 cycles of trastuzumab with capecitabine plus oxaliplatin. However, the primary lesion increased in size. Therefore, she underwent distal gastrectomy and D1+ lymphadenectomy with para-aortic lymph node sampling as a conversion surgery. The pathological diagnosis was T2N0M0, pStage ⅠB, and the primary cancer was Grade 1a owing to the chemotherapeutic effect. She survives without recurrence or postoperative adjuvant therapies 3 years after the surgery.
Databáze: OpenAIRE