[Metformin-associated hepatotoxicity]

Autor: S, Olivera-González, B, de Escalante-Yangüela, C, Velilla-Soriano, B, Amores-Arriaga, P, Martín-Fortea, M E, Navarro-Aguilar
Rok vydání: 2009
Předmět:
Zdroj: Medicina intensiva. 34(7)
ISSN: 0210-5691
Popis: Metformin is an oral biguanide widely used in the management of patients with type 2 diabetes. It produces non-specific gastrointestinal symptoms in 10-30% of the patients. Lactic acidosis is the most serious side effect, so it must not be administered to patients with renal, liver, or heart insufficiency. Only a few cases of hepatotoxicity due to this drug have been documented. We report the case of a patient with type 2 diabetes mellitus and recent use of metformin who developed serious liver injury, followed by a favorable evolution.
Databáze: OpenAIRE