[HPV DNA genotyping: A study of anogenital, head and neck and skin cancers in a population from west Algerian. HPV detection in different cancers from an Algerian population]
| Autor: | Amira, Nahet, Lamia, Boublenza, Hafida, Hassaine, Nabila, Masdoua, Jean-Luc, Prétet, Essaada, Belglaiaa, Christiane, Mougin |
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| Jazyk: | francouzština |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Aged 80 and over Male Human papillomavirus 16 Skin Neoplasms Vaginal Neoplasms Genotype Human papillomavirus 18 Vulvar Neoplasms Genital Neoplasms Female Tonsillar Neoplasms Uterine Cervical Neoplasms Middle Aged Anus Neoplasms Head and Neck Neoplasms Algeria DNA Viral Humans Female Laryngeal Neoplasms Papillomaviridae Aged |
| Zdroj: | Bulletin du cancer. 103(5) |
| ISSN: | 1769-6917 |
| Popis: | To investigate the prevalence of human papillomaviruses (HPV) in cancers located at different sites in patients from west Algerian and collected between 2010 and 2014.Extracted DNA from archival formaldehyde-fixed and paraffin-embedded tissues was provided from 39 anogenital cancers, 10 head and neck cancers and 36 skin cancers. The viral DNA was detected using the INNO-LiPA HPV Genotyping Extra(®) kit.The prevalence of HPV was 100% in cervical cancers, 40% in vaginal cancers, 17% in vulvar cancers, 33% in anal cancers, 0% in tonsil and larynx cancers and 6.4% in skin squamous cell carcinoma. In cervical cancers, the most prevalent genotypes were HPV16 (52%) and HPV18 (12%) as single infection.The overall results agree partially with literature. Extensive research is necessary to promote HPV vaccine to reduce in particular the burden of cervical cancer in Algeria. |
| Databáze: | OpenAIRE |
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