Hidden magicians of genome evolution
| Autor: | C Sandeep, Kumar, Sameera Fatima, Qureshi, Altaf, Ali, M L, Satyanarayana, Advithi, Rangaraju, A, Venkateshwari, Pratibha, Nallari |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Genome
Gene Transfer Horizontal Models Genetic Transcription Genetic Genome Human Cell Cycle Terminal Repeat Sequences food and beverages DNA Review Article Evolution Molecular structural & functional roles Enhancer Elements Genetic Dynamic component homology-dependent gene silencing evolution DNA Transposable Elements Animals Humans Gene Silencing transposable elements Promoter Regions Genetic horizontal transfer |
| Zdroj: | The Indian Journal of Medical Research |
| ISSN: | 0971-5916 |
| Popis: | Transposable elements (TEs) represent genome's dynamic component, causing mutations and genetic variations. Transposable elements can invade eukaryotic genomes in a short span; these are silenced by homology-dependent gene silencing and some functional parts of silenced elements are utilized to perform novel cellular functions. However, during the past two decades, major interest has been focused on the positive contribution of these elements in the evolution of genomes. The interaction between mobile DNAs and their host genomes are quite diverse, ranging from modifications of gene structure to alterations in general genome architecture and can be regarded as hidden magicians in shaping evolution of genomes. Some of the prominent examples that impressively demonstrate the beneficial impact of TEs on host biology over evolutionary time include their role in structure and functions of eukaryotic genomes. |
| Databáze: | OpenAIRE |
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