[The effect of x-ray irradiation on the production of interleukin-6 and tumor necrosis factor-alpha by mononuclear cells of the peripheral blood]

Autor:	M E, Komarovskaia, S I, Dryk, S I, Krivenko, L V, Karkanitsa
Rok vydání:	1993
Předmět:	Time Factors Interleukin-6 Tumor Necrosis Factor-alpha Leukocytes Mononuclear Humans Dose-Response Relationship Radiation In Vitro Techniques Phytohemagglutinins Cells Cultured
Zdroj:	Radiobiologiia. 33(1)
ISSN:	0033-8192
Popis:	The influence of X-radiation on production of interleukin-6 (IL-6) and alpha-tumor necrosis factor (TNF) has been investigated. Irradiation with doses of 45, 90 and 900 cGy was shown to increase considerably TNF and IL-6 production both in intact mononuclear cultures of human peripheral blood and in cultures stimulated by phytohemagglutinin. In addition to an absolute increase in the production, the stimulatory effect was manifested by earlier accumulation of IL-6 and TNF activities in supernatant fractions of the cultures under study.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d2cc236cd473c75641dfc6c8f08b6c86 https://pubmed.ncbi.nlm.nih.gov/8469751 Zobrazit plný text záznamu