| Autor: |
C, Watts, P A, Reid, M A, West, H W, Davidson |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Seminars in immunology. 2(4) |
| ISSN: |
1044-5323 |
| Popis: |
Monovalent antigen bound to membrane immunoglobulin on human B lymphoblastoid cells is endocytosed through coated pits and passes sequentially from a site which actively recycles membrane to the cell surface and then to a proteolytically active processing site. A high affinity of immunoglobulin for antigen precludes antigen dissociation following endocytosis and results in the processing of an antigen/Ig complex yielding an epitope-specific pattern of processing. Processing of the immunoglobulin also occurs and is enhanced by occupancy with monovalent antigen. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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