Autor: |
M A, Scheinberg, E, Chapira, M L, Fernandes, O, Hubscher |
Rok vydání: |
1996 |
Předmět: |
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Zdroj: |
Clinical and experimental rheumatology. 14(6) |
ISSN: |
0392-856X |
Popis: |
Adult onset Still's disease (AOSD) is an inflammatory disorder with elevated serum acute phase proteins. Interleukin-6 is a major contributor to the acute phase response. We therefore examined the serum levels of CRP, SAA and interleukin-6 in active and inactive AOSD.Active patients had significantly elevated CRP, SAA, and interleukin-6 values. After steroid treatment a marked reduction was observed in all three parameters. There was a close kinetics on the fluctuations of CRP and SAA, but not on IL-6.Acute phase proteins and IL-6 are useful markers of disease activity in AOSD. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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