The vitamin D metabolites 25(OH)D and 1,25(OH)

Autor:	K W, Ter Horst, R I, Versteeg, P W, Gilijamse, M T, Ackermans, A C, Heijboer, J A, Romijn, S E, la Fleur, R, Trinko, R J, DiLeone, M J, Serlie
Rok vydání:	2016
Předmět:	Adult Blood Glucose Cohort Studies Calcitriol Glucose Clamp Technique Humans Female Middle Aged Vitamin D Deficiency Calcifediol Obesity Morbid
Zdroj:	Diabetesmetabolism. 42(6)
ISSN:	1878-1780
Popis:	Vitamin D deficiency has been proposed to be involved in obesity-induced metabolic disease. However, data on the relationship between 25-hydroxycholecalciferol (25(OH)D) and insulin resistance have been inconsistent, and few studies have investigated the active vitamin D metabolite, 1,25-dihydroxycholecalciferol (1,25(OH)Serum levels of 25(OH)D and 1,25(OH)Sixteen subjects had circulating 25(OH)D levels50nmol/L, consistent with vitamin D deficiency, and 21 had normal 25(OH)D levels. There were no differences in either baseline characteristics or parameters of glucose metabolism and insulin action between the groups. Serum 25(OH)D, but not 1,25(OH)Obesity was associated with lower levels of circulating 25(OH)D, but not with the hormonally active metabolite 1,25(OH)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::d1fe6638be1a41783255b76edd86d558 https://pubmed.ncbi.nlm.nih.gov/27262368 Zobrazit plný text záznamu Full Text from ScienceDirect