| Autor: |
Iu E, Vinogradova, I A, Zamulaeva, V V, Pavlov, E I, Selivanova, V I, Deĭgin, S G, Smirnova, N V, Orlova, A S, Saenko |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Terapevticheskii arkhiv. 74(8) |
| ISSN: |
0040-3660 |
| Popis: |
To study influence of thymodepressin on the course of autoimmune cytopenia.Thymodepressin is a new synthetic hemoregulatory dipeptide (gamma-D-Glu-D-Trp). It was used for the treatment of 22 patients with autoimmune cytopenia.Hemoglobin levels were elevated in autoimmune hemolytic anemia and platelet levels were high in idiopathic thrombocytopenic purpura. A thymodepressin course resulted in a fall of total lymphocyte count and activated CD3+CD69+ lymphocytes.The above results, safety, absence of toxicity and allergenicity, parenteral and intranasal useability open perspectives for further studies of therapeutic action of thymodepressin as an immunodepressant in autoimmune processes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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