| Autor: |
John H, McDermott, Marc, Leach, Dwaipayan, Sen, Craig J, Smith, William G, Newman, Philip M, Bath |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Expert review of clinical pharmacology. 15(7) |
| ISSN: |
1751-2441 |
| Popis: |
Clopidogrel is an antiplatelet agent recommended for secondary prevention of ischemic stroke (IS) and transient ischemic attack (TIA). Conversion of clopidogrel to its active metabolite by hepatic cytochrome P450-2C19 (CYP2C19) is essential for the inhibition of the P2Y12 receptor and subsequent platelet aggregation to prevent thrombotic events.A systematic literature review retrieved articles, which describe the interaction betweenThere is good evidence that |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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