| Autor: |
H, Zarrınanbour, G, Keser, A, Dönmez, S, Çağırgan, F, Oksel, K, Aksu, M, Tombuloğlu |
| Rok vydání: |
2016 |
| Zdroj: |
Turkish journal of haematology : official journal of Turkish Society of Haematology. 16(4) |
| ISSN: |
1300-7777 |
| Popis: |
We investigated activated protein C resistance (aPCR) using modified activated partial thromboplastin time (aPTT) in 32 patients with Behçet's disease (BD) and 9 healthy controls. None of the healthy controls were found to have aPCR. However, 11 out of 32 Behçet's patients (34.3%) were found to have aPCR. The frequency of aPCR was increased to 44.4% among 18 Behçet's patients having a history of venous thrombosis. In the subgroup of 14 patients without venous thrombosis, aPCR frequency was %22.2. Our findings show that, besides other factors, aPCR may also predispose patients to venous thrombosis in BD. The detection of aPCR, using modified aPTT may serve as a routine screening test to determine the necessity of prophylactic anticoagulation reatment in patients with BD. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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