[Long term outcome following 26 surgical ampullectomies]
| Autor: | M, Ouaïssi, I, Sielezneff, A, Alves, N, Pirro, L, Heyries, S, Robitail, B, Consentino, M-J, Payan, P, Valleur, Y, Panis, B, Sastre |
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| Jazyk: | francouzština |
| Rok vydání: | 2006 |
| Předmět: |
Adenoma
Adult Male Ampulla of Vater Common Bile Duct Diseases Common Bile Duct Neoplasms Adenocarcinoma Middle Aged Granuloma Plasma Cell Survival Rate Treatment Outcome Adenomatous Polyposis Coli Cause of Death Somatostatinoma Humans Female Longitudinal Studies Neoplasm Recurrence Local Carcinoma in Situ Aged Follow-Up Studies Retrospective Studies |
| Zdroj: | Annales de chirurgie. 131(5) |
| ISSN: | 0003-3944 |
| Popis: | Pancreaticoduodenectomy (PD) is the standard surgical treatment for malignant ampullomas but is still associated with a mortality and morbidity still ranging from 0 to 10% and from 15 to 40%, respectively. Ampullectomy is an alternative to PD for benign ampulloma or, in high-risk patients, for invasive carcinoma. The aim of this study was to report early and long term results of surgical ampullectomy for presumed benign ampullomas.From 1981 to 2004, 26 patients from two institutions underwent surgical ampullectomy. Of the 26 patients, 8 had familial adenomatous polyposis (FAP). Surgical ampullectomy was indicated on a multisciplinary basis.Final pathological examination revealed 15 adenomas, 4 in situ adenocarcinomas, 2 endocrine tumors, and 5 other benign lesions. There was no postoperative mortality. Specific morbidity was 8% (N=2). Mean follow-up was 86+/-70 months (range: 3-204). Actuarial overall 5-year survival was 92%. There were 4 local recurrences (none in patients with FAP). Four patients died during follow-up (including 3 from initial disease).Ampullectomy is a good alternative to PD in case of benign or non-invasive malignant ampullary lesion, including in selected cases of FAP. |
| Databáze: | OpenAIRE |
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