| Autor: |
Gerson de A, Queiroz, Raimon R, da Silva, Anaque de O, Pires, Ryan Dos S, Costa, Neuza M, Alcântara-Neves, Thiago M, da Silva, Mauricio L, Barreto, Sergio C, Oliveira, Camila A, Figueirêdo |
| Rok vydání: |
2019 |
| Zdroj: |
Cytokine: X. 2(3) |
| ISSN: |
2590-1532 |
| Popis: |
Atopic asthma is a chronic lung disease of lower airways caused mainly due to action of T-helper (Th) 2 type cytokines, eosinophilic inflammation, mucus hypersecretion and airway remodelling. Interleukin (IL)-33 increases type 2 immunity polarization in airway playing critical role in eosinophilic asthma. On the other hand, NLRP3 inflammasome activation results in the release of caspase-1 (Casp-1) which, in its turn, promotes IL-33 inactivation. Recent studies have shown associations between |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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